Transfer In

General Description

Use this operation to bring a known amount of material, of known composition, from one vessel into another via an process intermediate stream. Note that the material is not modelled to be a direct process input. If you need to bring material into a vessel via an process input stream then use a Charge operation. If you don’t know the amount of material to be transferred in but instead the amount depends on some criterion (e.g. to achieve a certain volume level or concentration in the vessel) then use a Pull In operation instead.

This operation may result in VOC emissions if volatile compounds are involved; for more details, see Chapter 10  (Emissions).

Unit Procedure Availability

      Batch Vessel Procedure in a Reactor

      Batch Vessel Procedure in a Seed Reactor

      Batch Vessel Procedure in a Bioreactor

      Batch Vessel Procedure in a Seed Bioreactor

      Batch Vessel Procedure in a Disposable Bioreactor

      Batch Vessel Procedure in a Disposable Seed Bioreactor

      Batch Vessel Procedure in a Fermentor

      Batch Vessel Procedure in a Seed Fermentor

      Batch Vessel Procedure in a Disposable Bioreactor

      Inoculum Preparation Procedure in a Rocking Bioreactor

      Inoculum Preparation Procedure in a Roller Bottle

      Inoculum Preparation Procedure in a T-Flask

      Inoculum Preparation Procedure in a Shake Flask

      Inoculum Preparation Procedure in a Test Tube

      Microfiltration (Batch) Procedure

      Microfiltration (Feed and Bleed) Procedure

      Ultrafiltration (Batch) Procedure

      Ultrafiltration (Feed and Bleed) Procedure

      Reverse Osmosis (Batch) Procedure

      Reverse Osmosis (Feed and Bleed) Procedure

      Diafiltration Procedure

      Nutsche Filtration Procedure

      Centrifugation in a Basket Centrifuge (Top Discharge) Procedure

      Centrifugation in a Basket Centrifuge (Bottom Discharge) Procedure

      Tray Drying Procedure

      Freeze Drying Procedure

      Flash Evaporation Procedure

      Batch Distillation Procedure

      Batch Storage in a Blending Tank Procedure

      Batch Storage in a Flat Bottom Tank Procedure

      Batch Storage in a Receiver Tank Procedure

      Batch Storage in a Horizontal Tank Procedure

      Batch Storage in a Vertical-on-Legs Tank Procedure

      Batch Storage in a Drum Procedure

      Batch Storage in a Drum Procedure

      Batch Storage in a Disposable Generic Container Procedure

      Batch Storage in a Disposable Large Bag (on a Skid) Procedure

      Freezing-Thawing Procedure

      Mixing In a Batch Tumble Mixer Procedure

      Batch 1x1 Generic Box Procedure

      Batch 3x3 Generic Box Procedure

      Batch 5x5 Generic Box Procedure

      Batch 10x10 Generic Box Procedure

Material Inputs / Outputs

The operation combines material as found in the host vessel at the end of the previous operation (if any) and the material of the designated transfer in stream. The results of the operation are left as the equipment contents at the end of the charge operation.

Transfer In: Modeling Calculations

The modeling equations of a Transfer In operation are very simple. The only goal is to determine the transfer time or transfer rate using the following equation:

BatchVesselProcessTime00091.jpg 

eq. (A.37)

If the duration of this operation is matched up to another operation (master operation), then the setup time, process time and turnaround time are simply derived from the master operation.

Equipment Sizing

See Batch Vessel Operations: Equipment Sizing.

Vacuum Pump Power Consumption

See Vacuum Pump Auxiliary Equipment Calculations.

Transfer In: Interface

The interface of this operation has the following tabs:

      Oper. Cond’s, see Transfer In: Oper. Conds Tab

      Volumes, see Batch Vessel Operations: Volumes Tab

      Vent/Emissions, see Vessel Operations: Vent/Emissions Tab

      Labor, etc, see Operations Dialog: Labor etc. Tab

      Description, see Operations Dialog: Description Tab

      Batch Sheet, see Operations Dialog: Batch Sheet Tab

      Scheduling, see Operations Dialog: Scheduling Tab