Operating Mode
Batch/Semi-Continuous
Host Equipment
Emissions Port (Vent)
No
Special Input/Output Ports
Yes
A Microfiltration (Batch) Procedure can be created by selecting the following menu option:
Unit Procedures } Filtration } Microfiltration (Batch)
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Operating Mode |
Batch/Semi-Continuous |
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Host Equipment |
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Emissions Port (Vent) |
No |
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Special Input/Output Ports |
Yes |
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Batch microfiltration is used for solid-liquid separations (to remove micron-size particles). In bioprocessing, microfiltration is commonly used for cell harvesting, cell debris removal, and sterilization of cell culture media. The pore sizes of microfilter membranes usually range from 0.1 to 0.45 microns. In tangential microfiltration, cross flow parallel to the filter surface is used to enhance filtrate flux.
● Filtrate: the designated output port for the filtrate.
The following operation types are currently supported in the context of this unit procedure:
● Concentrate (Batch), see Batch Concentration (Batch Membrane Filtration)
● Flush, see Flush
● CIP, see Clean-In-Place (CIP)
● Hold, see Holding
● SIP, see Steam-In-Place (SIP)
The following procedures offer a similar functionality:
● Microfiltration (Feed and Bleed) Procedure
● Ultrafiltration (Batch) Procedure
● Reverse Osmosis (Batch) Procedure