Batch Vessel Operations: Volumes Tab

Variable Definitions, Ranges and Default Values

The following table shows a brief description of the variables appearing in this tab. The table also displays their default values and their generally acceptable range:

Symbol Key: ○ User-specified value (always input); ● Calculated value (always output); ◙ Sometimes input, sometimes output

Specification Choices / Comments

This interface is used by a number of batch vessel operations including:

●      Liquid transfer operations: Charge, Pull In, Pull Out, Transfer In and Transfer Out.

●      Batch reaction operations: Batch Stoichiometric Reaction, Batch Kinetic Reaction, Batch Equilibrium Reaction, Batch Stoichiometric Fermentation, Batch Kinetic Fermentation and Perfusion Stoichiometric Fermentation.

●      Other operations: Agitation, Batch Heating, Batch Cooling, Batch Crystallization, Batch Distillation, Batch Extraction / Phase Split, Sampling, Batch Component Splitting, Batch Vaporization / Solvent Switch, Rigorous Batch Vaporization / Solvent Switch and Load and Split.

In Design Mode, the value of the Maximum Allowable Working / Vessel Volume is used for sizing the vessel. If multiple operations in the same procedure recommend sizing values, the procedure selects the maximum.

In Rating mode, the value of the Maximum Allowable Working / Vessel Volume acts as a constraint that generates a warning when it is violated. The value of the Minimum Allowable Working / Vessel Volume always acts as a constraint (unless the “Ignore?” option is checked).

By default, the “Ignore” option is checked for operations don’t require heating or cooling (i.e., Charge, Pull In, Pull Out, Transfer In, Transfer Out, Batch Extraction / Phase Split, Sampling, Batch Component Splitting and Load and Split) since these operations may not need an agitator, and hence, they may not need to set a “Min Allowable Working to Vessel Volume Ratio” limit. For all other operations, the “Ignore” option is unchecked by default.