A Diafiltration Procedure can be created by selecting the following menu option:
Unit Procedures } Filtration } Diafiltration
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Operating Mode |
Batch/Semi-Continuous |
Host Equipment |
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Emissions Port (Vent) |
No |
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Special Input/Output Ports |
Yes |
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This procedures simulates the performance of a membrane diafiltration unit. Diafiltration can be preceded and followed by batch concentration operations. In diafiltration, water or some other solvent or buffer is added to the retentate to facilitate the removal of membrane-permeating species along with the water (or other solvent) during filtration.
● Diluant: the designated input port for the diluant.
● Filtrate: the designated output port for the filtrate.
The following operation types are currently supported in the context of this unit procedure:
● Concentrate (Batch), see Batch Concentration (Batch Membrane Filtration)
● Diafilter, see Diafiltration
● CIP, see Clean-In-Place (CIP)
● Flush, see Flush
● Hold, see Holding
● SIP, see Steam-In-Place (SIP)
The following procedures offer a similar functionality:
● Microfiltration (Batch) Procedure
● Ultrafiltration (Batch) Procedure
● Reverse Osmosis (Batch) Procedure