This operation model simulates batch crystallization in a stirred vessel. Crystallization can take place either by addition of a solvent, or by evaporation, or by simple cooling of the solution.
● Batch Vessel Procedure in a Reactor
● Batch Vessel Procedure in a Seed Reactor
● Batch Vessel Procedure in a Bioreactor
● Batch Vessel Procedure in a Seed Bioreactor
● Batch Vessel Procedure in a Disposable Bioreactor
● Batch Vessel Procedure in a Disposable Seed Bioreactor
● Batch Vessel Procedure in a Fermentor
● Batch Vessel Procedure in a Seed Fermentor
● Batch Vessel Procedure in a Disposable Bioreactor
● Inoculum Preparation Procedure in a Rocking Bioreactor
● Inoculum Preparation Procedure in a Roller Bottle
● Inoculum Preparation Procedure in a T-Flask
● Inoculum Preparation Procedure in a Shake Flask
● Inoculum Preparation Procedure in a Test Tube
● Batch 3x3 Generic Box Procedure
● Batch 5x5 Generic Box Procedure
● Batch 10x10 Generic Box Procedure
During crystallization, one (or more) components will be converted from their soluble forms into their crystallized forms. Therefore, in order to be able to achieve the desired crystallization effect, you must have defined two distinct components: one to represent the soluble form (e.g., CaSO4) and one to represent the crystallized form (e.g., CaSO4-crystal).
The user specifies the crystallization yield, yp, of the main soluble product component and identifies its crystallized form. The crystallization yields, yi, of all other components (i) that crystallize are specified as a function of the product crystallization yield by a second-degree polynomial equation:
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The heat of crystallization and the heat of evaporation should be specified at the reference temperature of 25 °C. If evaporation is considered, it is assumed that it takes place prior to crystallization.
See Batch Vessel Operations: Equipment Sizing.
See Vacuum Pump Auxiliary Equipment Calculations.
The interface of this operation has the following tabs:
● Oper. Cond’s, see Batch Crystallization: Oper. Conds Tab
● Volumes, see Batch Vessel Operations: Volumes Tab
● Crystal. Data, see Batch Crystallization: Crystallization Data Tab
● Vent/Emissions, see Reaction Operations: Vent/Emissions Tab
● Labor, etc, see Operations Dialog: Labor etc. Tab
● Description, see Operations Dialog: Description Tab
● Batch Sheet, see Operations Dialog: Batch Sheet Tab
● Scheduling, see Operations Dialog: Scheduling Tab