eq. (A.1)
The primary objective of this operation is to account for the time and power required for mixing the contents of a vessel using a built-in stirrer. The user may opt to specify directly the total amount of power consumed for the operation, or specify the power consumed per equipment unit which will be used to determine the actual total power once the number of units is known, or provide a specific power value (as power per volume) which will be used to determine the actual total power once the total liquid volume (at the start of the operation) is known.
This operation checks to make sure that the liquid level in the vessel is between the specified maximum and minimum limits.
● Batch Vessel Procedure in a Reactor
● Batch Vessel Procedure in a Seed Reactor
● Batch Vessel Procedure in a Bioreactor
● Batch Vessel Procedure in a Seed Bioreactor
● Batch Vessel Procedure in a Disposable Bioreactor
● Batch Vessel Procedure in a Disposable Seed Bioreactor
● Batch Vessel Procedure in a Fermentor
● Batch Vessel Procedure in a Seed Fermentor
● Batch Vessel Procedure in a Disposable Bioreactor
● Inoculum Preparation Procedure in a Rocking Bioreactor
● Inoculum Preparation Procedure in a Roller Bottle
● Inoculum Preparation Procedure in a T-Flask
● Inoculum Preparation Procedure in a Shake Flask
● Inoculum Preparation Procedure in a Test Tube
● Batch Storage in a Blending Tank Procedure
● Batch Storage in a Flat Bottom Tank Procedure
● Batch Storage in a Receiver Tank Procedure
● Batch Storage in a Horizontal Tank Procedure
● Batch Storage in a Vertical-on-Legs Tank Procedure
● Batch Storage in a Drum Procedure
● Batch Storage in a Drum Procedure
● Batch Storage in a Tote Procedure
● Batch Storage in a Disposable Large Bag (on a Skid) Procedure
● Batch 1x1 Generic Box Procedure
● Batch 3x3 Generic Box Procedure
● Batch 5x5 Generic Box Procedure
● Batch 10x10 Generic Box Procedure
The operation uses material as found in the host vessel at the end of the previous operation (if any). The results of the operation are left as the equipment contents at the end of the operation.
The duration of the operation is determined by its setup time, agitation (process) time, and turnaround time.The agitation time may be set by user or set by a master-slave relationship. If it is set by a master-slave relationship, SuperPro Designer’s simulation engine will match the setup time, the process time and the turnaround time of this operation (the ‘slave’) with the corresponding times of the reference operation (the ‘master’). For more details on scheduling of operations, see Chapter 7 (Scheduling) and Operations Dialog: Scheduling Tab. For more details on how to setup a master-slave relationship, see The Scheduling Tab.
The duration of the operation is used to determine the cycle time of the procedure and the volume of material that is processed per cycle. In design mode, the vessel is sized based on that volume and on the specified maximum allowable % volume. Note that if multiple operations in the same procedure recommend sizing values, the procedure selects the maximum. In rating mode, the maximum allowable % volume acts as a constraint that generates a warning when it is violated. The minimum allowable % volume always acts as a constraint.
In terms of power consumption, the following specification options are available:
a) Set Specific Power
b) Set Total Power
c) Set Power Per Unit
If option (a) is selected, the power consumed per volume of liquid processed is specified and the total power and power per unit are calculated. If option (b) is specified, the total power consumed by the operation is specified and the specific power and power per unit are calculated. If option (c) is selected, the power consumed per equipment unit is specified and the specific power and total power are calculated.
Based on the specified fraction of power that is dissipated into heat, the final temperature of agitated material is calculated as follows:
|
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eq. (A.1) |
where:
● f is the fraction of consumed power that is dissipated into heat
● P is the total power consumption
● t is the agitation time
● m is the total mass of agitated material
● cp is the specific heat capacity of agitated material
● Tf is the final temperature of agitated material (after agitation)
● Ti is the initial temperature of agitated material (before agitation)
● The vessel must contain material of non-zero volume and of liquid/solid phase. If the material is found to be of mixed phase, then only the liquid/solid volume is considered in the calculations.
● It is assumed that a specified fraction of power is dissipated into heat and raises the temperature of the vessel contents. Heat losses to the environment are ignored.
See Vacuum Pump Auxiliary Equipment Calculations.
The interface of this operation has the following tabs:
● Oper. Cond’s, see Agitation: Oper. Conds Tab
● Volumes, see Batch Vessel Operations: Volumes Tab
● Vent/Emissions, see Vessel Operations: Vent/Emissions Tab
● Labor, etc, see Operations Dialog: Labor etc. Tab
● Description, see Operations Dialog: Description Tab
● Batch Sheet, see Operations Dialog: Batch Sheet Tab
● Scheduling, see Operations Dialog: Scheduling Tab