Evacuation

General Description

This operation is used to reduce the pressure of a vessel to a final pressure below ambient (1 atm, by default). If the final pressure must be equal or higher to the ambient pressure, please use a Venting operation, instead.

This operation may result in VOC emissions if volatile compounds are present in the vessel; for more details, see Chapter 10  (Emissions).

Unit Procedure Availability

      Batch Vessel Procedure in a Reactor

      Batch Vessel Procedure in a Seed Reactor

      Batch Vessel Procedure in a Bioreactor

      Batch Vessel Procedure in a Seed Bioreactor

      Batch Vessel Procedure in a Disposable Bioreactor

      Batch Vessel Procedure in a Disposable Seed Bioreactor

      Batch Vessel Procedure in a Fermentor

      Batch Vessel Procedure in a Seed Fermentor

      Batch Vessel Procedure in a Disposable Bioreactor

      Inoculum Preparation Procedure in a Rocking Bioreactor

      Inoculum Preparation Procedure in a Roller Bottle

      Inoculum Preparation Procedure in a T-Flask

      Inoculum Preparation Procedure in a Shake Flask

      Inoculum Preparation Procedure in a Test Tube

      Nutsche Filtration Procedure

      Freeze Drying Procedure

      Batch Distillation Procedure

      Batch Storage in a Blending Tank Procedure

      Batch Storage in a Flat Bottom Tank Procedure

      Batch Storage in a Receiver Tank Procedure

      Batch Storage in a Horizontal Tank Procedure

      Batch Storage in a Vertical-on-Legs Tank Procedure

      Batch Storage in a Drum Procedure

      Batch Storage in a Drum Procedure

      Batch Storage in a Tote Procedure

      Batch Storage in a Disposable Generic Container Procedure

      Batch 1x1 Generic Box Procedure

      Batch 3x3 Generic Box Procedure

      Batch 5x5 Generic Box Procedure

      Batch 10x10 Generic Box Procedure

Evacuation: Modeling Calculations

The user specifies the final system pressure and the duration of this operation. The specified final pressure must be less than the initial pressure and less than the ambient pressure.

Note that the ambient pressure can be specified through the Reference Conditions dialog. To display this dialog, right-click on white space in the flowsheet and then select Reference Conditions... from the context menu that is displayed.

This operation affects the amount of gases in the freeboard space. The material balance calculations are done by assuming ideal gas behavior.

Vacuum Pump Auxiliary Equipment Calculations

To account for the power consumption of the vacuum pump required to reduce the pressure from ambient to final, you may specify the vacuum pump power consumption through the Vent/Emissions tab, or you may click on the Setup button to open the Vacuum Pump Power Consumption Dialog and choose a different specification option for the vacuum pump power, such as the option to calculate the power consumption based on a suitable compression model.

In addition, you may specify a vacuum pump (as an auxiliary equipment) (optional) to account for the vacuum pump’s capital and operating costs and to consider the vacuum pump in scheduling calculations.

For more details, see Vacuum Pump Auxiliary Equipment Calculations.

Evacuation: Interface

The interface of this operation has the following tabs:

      Oper. Cond’s, see Evacuation: Oper. Conds Tab

      Vent/Emissions, see Vessel Operations: Vent/Emissions Tab

      Labor, etc, see Operations Dialog: Labor etc. Tab

      Description, see Operations Dialog: Description Tab

      Batch Sheet, see Operations Dialog: Batch Sheet Tab

      Scheduling, see Operations Dialog: Scheduling Tab