The stoichiometric fermentation model can be used to simulate biotransformations when the reaction kinetics are unknown or unimportant but the mass stoichiometry is known and the extent of reaction can be specified or calculated based on the concentration of a reference component. The extent of reaction is defined as the fractional conversion of the limiting component.
● Continuous Stoichiometric Reaction Procedure in a Fermentor
See Batch Stoichiometric Fermentation: Modeling Calculations.
See Vessel Sizing (Continuous Operations).
The equipment purchase cost includes the cost of the vessel along with the agitator cost. If the vessel is checked as an ‘ASME Vessel’ (i.e., constructed according to standards published by the American Society of Mechanical Engineers) then it assumed to withstand vacuum to 35 psig and its purchase cost is penalized by 20% over the base vessel cost. If the operating pressure of the vessel is set to a pressure higher than 3 atm, then the vessel’s purchase cost is penalized by an 80% increase over the base cost.
See Vacuum Pump Auxiliary Equipment Calculations.
The interface of this operation has the following tabs:
● Oper. Cond’s, see Continuous Fermentation Operations: Oper. Conds Tab
● Volumes, see Continuous Vessel Operations (Design Mode): Volumes Tab and Continuous Vessel Operations (Rating Mode): Volumes Tab
● Reactions, see Stoichiometric Reaction/Fermentation Operation: Reactions Tab
● Split, see Continuous Reaction / Storage Operations: Split Tab
● Vent/Emissions, see Reaction Operations: Vent/Emissions Tab
● Labor, etc, see Operations Dialog: Labor etc. Tab
● Description, see Operations Dialog: Description Tab
● Batch Sheet, see Operations Dialog: Batch Sheet Tab
● Scheduling, see Operations Dialog: Scheduling Tab