Batch Extraction / Phase Split: Mat. Balance Tab (Based on Partition Coefficients)

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Variable Definitions, Ranges and Default Values

The following table shows a brief description of the variables appearing in this tab. The table also displays their default values and their generally acceptable range:

Variable

Default Value

Range

 

Partition Coefficients (Ki)
Set this value for available non-solvent components.

0.0

Positive

Split %
The percentage of a component that is split to the selected (top or bottom) phase.

0.0

0-100

Light Phase Solvent Name
Indicates the component that is used as the light phase solvent in case that a two-solvent system is selected. Click on the list box to bring up a list of available components in order to select one.

<none>

Any Pure Component

Solubility in Light Phase (g/L)
The solubility of the heavy phase solvent in the light phase.

0.0

Positive

Heavy Phase Solvent Name
Indicates the component that is used as the heavy phase solvent in case that a two-solvent system is selected. Click on the list box to bring up a list of available components in order to select one.

<none>

Any Pure Component

Solubility in Heavy Phase (g/L)
The solubility of the light phase solvent in the heavy phase.

0.0

Positive

Common Solvent
Indicates the component that is used as solvent in case that a single-solvent system is selected. Click on the list box to bring up a list of available components in order to select one.

<none>

Any Pure Component

Fraction in Top (Light) Phase
The fraction of solvent in the light phase in case that a single-solvent system is selected.

0.4

0-1

Product Component Name
Indicates the product component. Click on the list box to bring up a list of available components in order to select one.

<none>

Any Pure Component

Recovery Yield (%)
The product recovery yield.

0.0

0-100

Symbol Key: User-specified value (always input); Calculated value (always output); Sometimes input, sometimes output

Specification Choices / Comments

The following list describes the available specification choices in this tab; for more details on how these are implemented, see Batch Extraction / Phase Split: Modeling Calculations.

Common solvent systems...

Common solvent systems (e.g., aqueous two-phase systems) are commonly used in biotechnology to recover and purify proteins and other biological molecules.